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美國(guó)食品藥品監(jiān)管局表示:電子煙或?qū)е掳d癇

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2019年04月10日

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The Food and Drug Administration just issued aspecial announcement about a new health risk thatthey worry may be linked to e-cigarettes: seizures.

美國(guó)食品藥品監(jiān)管局剛剛發(fā)布一則特殊聲明:他們擔(dān)心電子煙或?qū)е滦碌慕】碉L(fēng)險(xiǎn)--癲癇。

Since June 2018, the agency received what it called"a recent uptick" in reports where users describehaving seizures that may be connected with their e-cigarette use. The FDA collects information aboutvape safety risks through their Safety ReportingPortal, where people who use e-cigarettes can sharetheir experiences. Between reports via that portal and from poison control centers, the FDAcounted 35 reports of seizures between 2010 and early 2019 that may be related to vaping. Most of those, it said, involved "youth or young adult users."

自2018年6月以來(lái),該機(jī)構(gòu)收到了其所謂的"近期上升"報(bào)告。報(bào)告指出,電子煙用戶(hù)稱(chēng)他們癲癇發(fā)作或與抽電子煙相關(guān)。美國(guó)食品藥品監(jiān)管局通過(guò)其安全報(bào)告通道收集了關(guān)于電子煙安全風(fēng)險(xiǎn)的信息,電子煙用戶(hù)會(huì)通過(guò)安全報(bào)告通道分享個(gè)人經(jīng)歷。透過(guò)來(lái)自安全報(bào)告通道的報(bào)告及中毒控制中心的報(bào)告,美國(guó)食品藥品監(jiān)管局發(fā)現(xiàn),自2010年至2019年初,共計(jì)35份癲癇報(bào)告與電子煙相關(guān)。其中,大多數(shù)報(bào)告表示,涉及了"青少年或年輕成人用戶(hù)。"

 

美國(guó)食品藥品監(jiān)管局表示電子煙或?qū)е掳d癇.jpg

 

We know that nicotine poisoning can cause seizures, like when people swallow vape juice. But the FDA doesn't know yet what the relationship between seizures and vaping is here, saysFDA Commissioner Scott Gottlieb in a statement today. Some of these seizures might beunconnected, or some might be caused by inhaling massive amounts nicotine. That seemsless plausible, says Peter Chai, a medical toxicologist at Brigham and Women's Hospital inBoston. "I think exposure (skin contact or oral) in children, or vaping exposure in youngerindividuals (adolescents through which we've seen a large increase in e-cig use), might beaccounting or the increase in these seizures," he says in an email to The Verge.

我們知道,尼古丁中毒會(huì)導(dǎo)致癲癇,就像喝煙油一樣。但美國(guó)食品藥品監(jiān)管局并不清楚癲癇與電子煙之間的關(guān)系,美國(guó)食品藥品監(jiān)管局局長(zhǎng)斯科特·戈特利布在今日發(fā)布的聲明中說(shuō)道。有些癲癇發(fā)作與吸入大量尼古丁無(wú)關(guān),而有些則正是因?yàn)槲氪罅磕峁哦∫鸬?。波士頓布萊根婦女醫(yī)院(Brigham and Women'sHospital)的醫(yī)學(xué)毒理學(xué)家彼得·柴說(shuō),這似乎是不合理的。"我認(rèn)為兒童接觸(皮膚或口腔接觸),或年輕人接觸電子煙(青少年--吸電子煙的青少年越來(lái)越多),可能是導(dǎo)致癲癇發(fā)作的原因,"他在發(fā)給The Verge雜志的一封郵件中寫(xiě)道。

"To get enough nicotine in your body to cause seizures by smoking cigarettes is well-nighimpossible," says medical toxicologist Edward W. Boyer, an associate professor of emergencymedicine at Brigham and Women's Hospital. But similar cases of nicotine-related seizureshave been linked to eating it. Boyer thinks it's plausible that e-cigarettes could deliver enoughnicotine to do the same. The truth is, there's not much data to go on. And for now, the FDA'sGottlieb says, "We can't yet say for certain that e-cigarettes are causing these seizures."

"通過(guò)吸煙使體內(nèi)有足夠的尼古丁引發(fā)癲癇幾乎是不可能的,"布萊根婦女醫(yī)院的緊急醫(yī)學(xué)副教授、醫(yī)學(xué)毒理學(xué)家愛(ài)德華·博耶爾說(shuō)道。但與尼古丁相關(guān)的癲癇發(fā)作的類(lèi)似病例與攝入尼古丁相關(guān)。博耶爾認(rèn)為電子煙無(wú)法帶來(lái)如此量大的尼古丁。事實(shí)是,可供繼續(xù)研究的數(shù)據(jù)并不多。就目前而言,美國(guó)食品藥品監(jiān)管局局長(zhǎng)戈特利布說(shuō)道,"我們尚不能確定,電子煙會(huì)導(dǎo)致癲癇發(fā)作。"


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