A team of researchers from China, Britain and Bangladesh converted pluripotent stem cells, or an "adult" version of early embryonic cells, back to a more "juvenile" version of cells with developmental potential, tantamount to fertilized eggs in their day 3 developmental stage.
由中國、英國和孟加拉國的科學家組成的研究團隊將人類多能干細胞,即“成年”版本的早期胚胎細胞,轉化成具有發(fā)育潛力的、更“年輕”的干細胞,即相當于受精卵發(fā)育3天狀態(tài)的全能干細胞。
Totipotent 8-cell stage embryo-like cells recreate the embryonic state of a fertilized egg after only three divisions, making them the youngest human cells acquired in vitro ever known, Li Wenjuan from the Chinese Academy of Sciences said.
中國科學院的李文娟博士表示,這些全能性的8細胞期胚胎樣細胞重建了受精卵僅分裂3次后的胚胎狀態(tài),這是迄今為止在體外誘導獲得的“最年輕”的人類細胞。
Cells described as "totipotent" mean that they have the potential to create all types of cells within embryonic and extra-embryonic tissues, according to researchers.
據介紹,全能性細胞意味著它們有潛力分化出胚胎和胚胎外組織中所有類型的細胞。
"These cells can not only differentiate into placental tissue but also potentially develop into more mature organs," Li said.
李文娟博士說,這種細胞可以分化為胎盤組織,并可能發(fā)育為更成熟的各類身體組織。
Ethical review had given clearance to the relevant study.
該研究已通過倫理審查。