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《考研英語閱讀理解100篇 基礎(chǔ)版》第7章 醫(yī)藥類 Unit 85

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2019年01月23日

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Shortages of flu vaccine are nothing new in America,but this year's is a whopper.Until last week,it appeared that 100 million Americans would have access to flu shots this fall.Then British authorities,concerned about quality-control problems at a production plant in Liverpool,barred all further shipments by the Chiron Corp.Overnight,the U.S.vaccine supply dwindled by nearly half—and federal health officials found themselves making an unusual plea.Instead of beseeching us all to get vaccinated,they’re now urging most healthy people between the ages of 2 and 64 not to.“This re-emphasizes the fragility of our vaccine supply,” says Dr.Martin Myers of the National Network for Immunization Information,“and the lack of redundancy in our system.” 
Why is such a basic health service so easily knocked out? Mainly because private companies have had little incentive to pursue it.To create a single dose of flu vaccine,a manufacturer has to grow live virus in a 2-week-old fertilized chicken egg,then crack the egg,harvest the virus and extract the proteins used to provoke an immune response.Profit margins are narrow,demand is fickle and,because each year's flu virus is different,any leftover vaccine goes to waste.As a result,the United States now has only two major suppliers (Chiron and Aventis Pasteur)—and when one of them runs into trouble,there isn’t much the other can do about it.“A vaccine maker can’t just call up and order 40 million more fertilized eggs,” says Manon Cox,of Connecticut-based Protein Sciences Corp.“There's a whole industry that's scheduled to produce a certain number of eggs at a certain time.” 
Sleeker technologies are now in the works,and experts are hoping that this year's fiasco will speed the pace of innovation.The main challenge is to shift production from eggs into cell cultures—a medium already used to make most other vaccines.Flu vaccines are harder than most to produce this way,but several biotech companies are now pursuing this strategy,and one culture-based product(Solvay Pharmaceuticals’ Invivac)has been cleared for marketing in Europe. 
For America,the immediate challenge is to make the most of a limited supply.The government estimates that 95 million people still qualify for shots under the voluntary restrictions announced last week.That's nearly twice the number of doses that clinics will have on hand,but only 60 million Americans seek out shots in a normal year.In fact,many experts are hoping the shortage will serve as an awareness campaign—encouraging the people who really need a flu shot to get one. 
注(1):本文選自Newsweek; 
注(2):本文習(xí)題命題模仿對象:第1~4題分別模仿1997年真題Text 3第1~4題,第5題模仿1997年真題Text 4第4題。 
1.Shortages of flue vaccine show that ______. 
A) America relies too much on foreign suppliers 
B) the demand of flue vaccines is high this year 
C) quality problem is a serious problem in flu vaccine production 
D) the supply of flu vaccines is rather weak and America has no back-up measures to make it up 
2.The word“cleared” (Line 5,Paragraph 3)might mean ______. 
A) permitted 
B) removed 
C) proved 
D) produced 
3.Private companies have little interest in producing flu vaccines because of ______. 
A) complicated process,high cost,low profit and high risk 
B) shortages of fertilized chicken eggs 
C) difficulty in growing live virus 
D) fast changing of flu virus 
4.From the last paragraph we can infer that ______. 
A) the government hopes to solve the problem by way of volunteer restrictions 
B) more than 47 million Americans who are qualified to get flu vaccine shots cannot get them this year 
C) America needs not to worry about a limited supply of flu vaccines this year 
D) normally only a small percentage of American population gets flu vaccine shots each year 
5.According to the passage,which of the following is TRUE? 
A) All Americans are persuaded not to get vaccinated this year. 
B) The big problem in innovating flu vaccine's producing technique is how to grow virus in a new way. 
C) More flu vaccines cannot be produced in a short time because private companies refuse to produce more. 
D) Flu vaccines are easier than most vaccines to produce through cell cultures. 

流感疫苗短缺在美國不足為奇,但今年的短缺傳聞卻是一個彌天大謊。到上周為止,好像還有1億美國人能在今年秋季接種流感疫苗。緊接著,英國當(dāng)局因為擔(dān)心一家位于利物浦的生產(chǎn)廠的質(zhì)量控制問題而禁止所有Chiron Corp公司的產(chǎn)品供應(yīng)。一夜之間,美國的疫苗供應(yīng)量減少了近一半——而聯(lián)邦衛(wèi)生官員也發(fā)現(xiàn)他們正在提出一項不同尋常的請求:不是請求我們?nèi)プ⑸湟呙纾嵌卮倌切┠挲g在2~64歲之間的絕大多數(shù)健康人不去注射疫苗。“這再次凸顯出我們疫苗供應(yīng)的脆弱性,”全國免疫信息網(wǎng)的馬丁·邁爾斯醫(yī)生說,“此外,我們也沒有必要的補救機制。” 
為什么這種基本的保健服務(wù)會如此不堪一擊呢?主要原因是私人公司生產(chǎn)積極性不高。生產(chǎn)每一份流感疫苗,生產(chǎn)商都要在一枚受精兩星期的雞蛋中培育活病毒,然后打破雞蛋,提取病毒和用來激發(fā)免疫反應(yīng)的蛋白質(zhì)。利潤率低,需求不穩(wěn)定,此外由于每年的流感病毒不同,剩余的疫苗只能報廢。因此美國目前只有兩家大的供應(yīng)商(Chiron Corp和Aventis Pasteur)——當(dāng)其中一家公司遇到麻煩時,另一家公司也無能為力。“疫苗生產(chǎn)商根本不可能打個電話多要4000萬個受精雞蛋,”在康涅狄格一家蛋白質(zhì)科學(xué)公司工作的馬農(nóng)·考克斯說,“整個雞蛋生產(chǎn)都是按計劃進行的。什么時間生產(chǎn)多少雞蛋都是已經(jīng)預(yù)先計劃好的。” 
目前的生產(chǎn)已經(jīng)采用更好的技術(shù)。專家們希望今年的教訓(xùn)能夠加快技術(shù)革新的步伐。最大的挑戰(zhàn)是如何將疫苗生產(chǎn)從雞蛋培育轉(zhuǎn)向細(xì)胞培育——該技術(shù)已經(jīng)廣泛應(yīng)用于其他大部分疫苗的生產(chǎn)。用細(xì)胞培育技術(shù)生產(chǎn)流感疫苗比生產(chǎn)其他大部分疫苗難度更大。盡管如此,幾家生物技術(shù)公司正在進行這方面的嘗試。索馬爾Invivac醫(yī)藥公司研制的一種基于細(xì)菌培育技術(shù)的產(chǎn)品已經(jīng)獲準(zhǔn)在歐洲銷售。 
對美國來說,當(dāng)務(wù)之急是要利用好有限的流感疫苗。政府預(yù)計,盡管上周發(fā)布了自愿限制公告,仍有9500萬人有資格注射疫苗。這個數(shù)字幾乎是醫(yī)院臨床流感疫苗庫存量的兩倍。但正常情況下,每年僅有6000萬美國人接種流感疫苗。事實上,許多專家希望這次疫苗短缺問題能成為一次提高公民道德意識的活動——鼓勵那些確實需要注射疫苗的人們?nèi)プ⑸洹?nbsp;
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